The mechanisms involved in neuropathic pain are complex and involve both peripheral and central pathophysiologic phenomenon. For the Consumer. Applies to clomipramine: oral capsule. Along with its needed effects, clomipramine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Anafranil ™ (clomipramine hydrochloride) Capsules USP is an antiobsessional drug that belongs to the class (dibenzazepine) of pharmacologic agents known as tricyclic antidepressants. Spinal Cord and Cervical Nerve Roots Nerve impulses travel to and from the brain through the spinal cord to a specific location by way of the peripheral nervous system (PNS). Antidepressants are a class of drugs that reduce symptoms of depressive disorders by correcting chemical imbalances of neurotransmitters in the brain. An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain. Analgesic drugs act in various ways on the peripheral and central nervous systems. Antidepressants are a staple in the treatment of many chronic pain conditions, including arthritis, nerve damage, headache and low back pain. Defines the medication nortriptyline (Pamelor, Aventyl) a drug used to elevate the mood of patients with depression. Article includes descriptions, uses, drug interactions, and side effects. Addison's Disease --hypoadrenocorticism. Addison's Disease is hypoadrenocorticism, the opposite of Cushing's Disease. For general information about Addison's Disease, see this webpage. A local anesthetic (LA) is a medication that causes absence of pain sensation. When it is used on specific nerve pathways (local anesthetic nerve block), paralysis (loss of muscle power) also can be achieved.